Description

4-Bromothiophen-3-Amine is a versatile brominated thiophene derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amine and a bromine substituent on the thiophene ring, makes it an essential intermediate for constructing complex heterocyclic systems. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with tailored activity profiles.
• Material Science: Monomer or intermediate for the development of conductive polymers, organic semiconductors, and advanced electronic materials.
• Ligand and Catalyst Development: Used to synthesize novel ligands for transition metal catalysis and organocatalysts.
• Dye and Pigment Chemistry: Intermediate for producing specialized dyes and functional pigments.
• Academic and Contract Research: Fundamental reagent for methodological development and exploratory chemistry in university and CRO laboratories.

Basic Information

Product Name	4-Bromothiophen-3-Amine
CAS No.	161833-43-8
Molecular Formula	C4H4BrNS
Molecular Weight	178.05 g/mol
Synonyms	3-Amino-4-bromothiophene; 4-Bromo-3-thiophenamine; 4-Bromothiophen-3-ylamine; 3-Thiophenamine, 4-bromo-; 4-Bromo-3-aminothiophene; 3-Amino-4-bromothiophene; 4-Bromothiophene-3-amine
EINECS	Contact for details

Quality Control

Our 4-Bromothiophen-3-Amine is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for impurity profiling, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO 9001 compliant production for applications requiring stringent traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.