Description

3-Amino-4-Bromo-Thiophene-2-Carboxylicacidmethylester is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides, herbicides, and fungicides, leveraging its thiophene core for bioactivity.
• Material Science Research: Serves as a building block for creating advanced organic electronic materials, such as conductive polymers and organic semiconductors.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized dyes and pigments where the bromo and amino groups allow for further functionalization and color tuning.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create more complex biaryl and conjugated systems.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	3-Amino-4-Bromo-Thiophene-2-Carboxylicacidmethylester
CAS No.	161833-42-7
Molecular Formula	C6H6BrNO2S
Molecular Weight	236.09 g/mol
Synonyms	Methyl 3-amino-4-bromothiophene-2-carboxylate; 4-Bromo-3-aminothiophene-2-carboxylic acid methyl ester; 3-Amino-4-bromothiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-4-bromo-, methyl ester; Methyl 4-bromo-3-aminothiophene-2-carboxylate; 161833-42-7; 3-Amino-4-bromo-2-thiophenecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Bromo-Thiophene-2-Carboxylicacidmethylester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and scale-up. Certificates of Analysis (COA) with full batch traceability are provided to guarantee consistent quality and supply reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This product is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.