Description

Cyclohexanecarboxylic Acid, 2-Amino-, Methyl Ester, (1R,2S)- (9Ci) is a chiral, non-racemic intermediate of significant importance in asymmetric synthesis. Its defined stereochemistry at the 1 and 2 positions of the cyclohexane ring makes it a valuable building block for the production of enantiomerically pure compounds. This high-purity intermediate is primarily sought by pharmaceutical and agrochemical research and development organizations for the synthesis of active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides, where specific stereochemistry can be critical for biological activity and environmental safety.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the development of novel chiral ligands and organocatalysts used in stereoselective transformations.
• Fine Chemical and Specialty Chemical Production: Employed in the manufacture of high-value, complex molecules for flavors, fragrances, and advanced materials.
• Academic and Industrial Research: A valuable tool compound in medicinal chemistry and synthetic methodology development for constructing complex, stereodefined molecular architectures.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-Amino-, Methyl Ester, (1R,2S)- (9Ci)
CAS No.	161618-52-6
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(1R,2S)-2-Aminocyclohexanecarboxylic Acid Methyl Ester; Methyl (1R,2S)-2-Aminocyclohexanecarboxylate; (1R,2S)-Methyl 2-aminocyclohexanecarboxylate; trans-2-Aminocyclohexanecarboxylic Acid Methyl Ester (specified enantiomer); (1R,2S)-2-Amino-1-cyclohexanecarboxylic Acid Methyl Ester; Chiral Cyclohexane Ester Intermediate; CAS 161618-52-6
EINECS	Contact for details

Quality Control

Our production of Cyclohexanecarboxylic Acid, 2-Amino-, Methyl Ester, (1R,2S)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is fully characterized and tested using advanced analytical techniques including chiral HPLC, GC, and NMR to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.