Description

17-(Cyclopropylmethyl)-6,7-Dehydro-4,5-Epoxy-3-Benzyloxy-14-Hydroxy-6,7,2',3'-Indolomorphinan is a complex, high-purity synthetic organic compound belonging to the indolomorphinan class. It serves as a critical pharmaceutical intermediate and reference standard for research and development in medicinal chemistry. This compound is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the synthesis and study of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of advanced active pharmaceutical ingredients (APIs) targeting neurological and pain management pathways.
• Reference Standard for R&D: Used as a high-purity analytical standard in method development, validation, and quality control within pharmaceutical research laboratories.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates with optimized efficacy and safety profiles.
• Biochemical Assay Development: Employed in the development of in vitro screening assays to study receptor binding affinity and functional activity.
• Academic Research: Used by universities and research institutes for fundamental studies in organic synthesis, pharmacology, and neurochemistry.

Basic Information

Item	Details
Product Name	17-(Cyclopropylmethyl)-6,7-Dehydro-4,5-Epoxy-3-Benzyloxy-14-Hydroxy-6,7,2',3'-Indolomorphinan
CAS No.	161532-22-5
Molecular Formula	C30H30N2O4
Molecular Weight	482.57 g/mol
Synonyms	17-Cyclopropylmethyl-6,7-dehydro-4,5α-epoxy-3-benzyloxy-14-hydroxy-6,7:2',3'-indolomorphinan; 3-Benzyloxy-17-cyclopropylmethyl-6,7-dehydro-4,5α-epoxy-14-hydroxy-6,7:2',3'-indolomorphinan; 6,7-Dehydro-4,5α-epoxy-3-benzyloxy-14-hydroxy-17-cyclopropylmethyl-6,7:2',3'-indolomorphinan; Indolomorphinan derivative (CAS 161532-22-5); 3-O-Benzyl-17-cyclopropylmethyl-6,7-dehydro-4,5α-epoxy-14-hydroxy-6,7:2',3'-indolomorphinan
EINECS	Contact for details

Quality Control

Our 17-(Cyclopropylmethyl)-6,7-Dehydro-4,5-Epoxy-3-Benzyloxy-14-Hydroxy-6,7,2',3'-Indolomorphinan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.