Description

(S)-1-Iodo-2-(Boc-Amino)-3-Methylbutane is a high-purity chiral building block featuring a protected amino group and a reactive iodo handle. This compound is critical for the stereoselective synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily used by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing peptidomimetics and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Peptidomimetic Synthesis: Used to introduce non-natural, branched-chain amino acid analogs into peptide backbones to enhance metabolic stability and bioavailability.
• Agrochemical Research: Building block for creating chiral active ingredients with specific biological activity in crop protection products.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis.
• Chemical Biology Probes: Utilized in the synthesis of labeled or tagged molecules for studying biological pathways and protein interactions.
• Academic Research: Employed in university and institutional labs for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(S)-1-Iodo-2-(Boc-Amino)-3-Methylbutane
CAS No.	161529-21-1
Molecular Formula	C10H20INO2
Molecular Weight	313.18 g/mol
Synonyms	(S)-1-Iodo-2-((tert-butoxycarbonyl)amino)-3-methylbutane; (S)-2-((tert-Butoxycarbonyl)amino)-3-methyl-1-iodobutane; (S)-N-Boc-2-amino-3-methyl-1-iodobutane; (S)-Boc-Val-Iodide; (S)-tert-Butyl (1-iodo-3-methylbutan-2-yl)carbamate; (S)-Boc-2-amino-3-methylbutyl iodide; (S)-BocNH-Val-CH2I; (S)-1-Iodo-2-(Boc-amino)-3-methylbutane
EINECS	Contact for details

Quality Control

Our (S)-1-Iodo-2-(Boc-Amino)-3-Methylbutane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing purity, assay, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere for long-term stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.