Description

Ethyl 6-Bromo-2-oxo-2,3-dihydro-1H-1,3-benzimidazole-1-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated benzimidazole core structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific therapeutic pathways. It is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel compounds with enhanced biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those with benzimidazole-based pharmacophores for antiviral, anticancer, or anti-inflammatory applications.
• Agrochemical Research: Serves as a building block for developing new fungicides, herbicides, or plant growth regulators that leverage the bioactive benzimidazole scaffold.
• Organic Synthesis & Material Science: Used in academic and industrial research to construct complex heterocyclic systems for functional materials or as a ligand in catalytic processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of tailored compounds under cGMP conditions for clinical trials.

Basic Information

Product Name	Ethyl 6-Bromo-2-oxo-2,3-dihydro-1H-1,3-benzimidazole-1-carboxylate
CAS No.	161468-52-6
Molecular Formula	C10H9BrN2O3
Molecular Weight	285.10 g/mol
Synonyms	6-Bromo-1-(ethoxycarbonyl)-1,3-dihydro-2H-benzimidazol-2-one; Ethyl 6-bromo-2-oxo-1,3-dihydrobenzimidazole-1-carboxylate; 1H-Benzimidazole-1-carboxylic acid, 6-bromo-2,3-dihydro-2-oxo-, ethyl ester; 6-Bromo-1-carbethoxy-2-benzimidazolinone; 161468-52-6; Ethyl 6-bromo-2-oxobenzimidazole-1-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-2-oxo-2,3-dihydro-1H-1,3-benzimidazole-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.