Description

(3αr,7αr)-1,3-Dimethyl-2-(1-Piperidinyl)Octahydro-1H-1,3,2-Benzodiazaphosphole 2-Oxide is a specialized heterocyclic organophosphorus compound featuring a benzodiazaphosphole core. This molecule is valued for its role as a key chiral intermediate or ligand in advanced synthetic chemistry, particularly in asymmetric catalysis and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex, high-value target molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring chiral phosphorus centers.
• Asymmetric Catalysis Ligand: Used as a chiral ligand or catalyst precursor in transition metal-catalyzed reactions, such as hydrogenation or cross-coupling, to induce enantioselectivity.
• Agrochemical Synthesis: Employed in the research and development of advanced pesticides and herbicides where its unique structure can contribute to biological activity.
• Organocatalyst: Functions as a catalyst in organic transformations that benefit from its nucleophilic or basic properties at the phosphorus or nitrogen sites.
• Chemical Biology Probe: Utilized in academic and industrial research to study enzyme inhibition or as a molecular scaffold in probe design.
• Material Science Research: Investigated as a monomer or additive for creating novel polymers with specific electronic or coordination properties.

Basic Information

Product Name	(3αr,7αr)-1,3-Dimethyl-2-(1-Piperidinyl)Octahydro-1H-1,3,2-Benzodiazaphosphole 2-Oxide
CAS No.	161390-52-9
Molecular Formula	C14H28N3OP
Molecular Weight	285.37 g/mol
Synonyms	1,3-Dimethyl-2-(piperidin-1-yl)octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide; (3aR,7aR)-1,3-Dimethyl-2-(1-piperidinyl)octahydro-1H-1,3,2-benzodiazaphosphole 2-oxide; (3aR,7aR)-1,3-Dimethyl-2-(piperidin-1-yl)hexahydro-1H-1,3,2-benzodiazaphosphole 2-oxide; Chiral Benzodiazaphosphole Oxide; DMPO Ligand (context-specific); Octahydro-1,3,2-benzodiazaphosphole derivative
EINECS	Contact for details

Quality Control

Our (3αr,7αr)-1,3-Dimethyl-2-(1-Piperidinyl)Octahydro-1H-1,3,2-Benzodiazaphosphole 2-Oxide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.