Description

3-(2-Chloro-1H-Indol-3-Yl)-Acrylic Acid CAS NO 161125-08-2 is a high-purity, functionalized indole derivative that serves as a critical advanced pharmaceutical intermediate and key building block in organic synthesis. Its unique molecular structure, featuring both an indole core and an acrylic acid moiety, makes it indispensable for constructing complex molecules with specific biological activities. This compound is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the development of novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its bioactive indole scaffold.
• Organic Synthesis Building Block: Employed in coupling reactions (e.g., Suzuki, Heck) and cyclization processes to create complex heterocyclic compounds.
• Material Science: Investigated as a monomer or functional component in the development of specialty polymers and advanced organic materials.
• Biochemical Research: Serves as a tool compound or a fluorescent probe precursor in biochemical and pharmacological studies.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for method development and discovery chemistry.

Basic Information

Product Name	3-(2-Chloro-1H-Indol-3-Yl)-Acrylic Acid
CAS No.	161125-08-2
Molecular Formula	C11H8ClNO2
Molecular Weight	221.64 g/mol
Synonyms	(E)-3-(2-Chloro-1H-indol-3-yl)acrylic acid; 3-(2-Chloro-1H-indol-3-yl)-2-propenoic acid; 2-Chloro-3-(2-carboxyvinyl)indole; 2-Chloroindole-3-acrylic acid; (2E)-3-(2-Chloro-1H-indol-3-yl)prop-2-enoic acid; 3-(2-Chloroindol-3-yl)acrylic Acid; 161125-08-2; 2-Chloro-1H-indole-3-acrylic acid
EINECS	Contact for details

Quality Control

Our production of 3-(2-Chloro-1H-Indol-3-Yl)-Acrylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.