Description

3-Acetyl-5-Chlorothiophene-2-Sulfonamide is a high-purity, multi-functional sulfonamide derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique thiophene-sulfonamide-acetyl structure makes it a valuable building block for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for enzyme inhibitors and receptor modulators.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: An essential building block for synthesizing more complex sulfonamide derivatives and fused heterocyclic systems.
• Biochemical Research: Employed as a tool compound in biochemical assays and for studying protein-ligand interactions.

Basic Information

Product Name	3-Acetyl-5-Chlorothiophene-2-Sulfonamide
CAS No.	160982-10-5
Molecular Formula	C6H6ClNO3S2
Molecular Weight	239.70 g/mol
Synonyms	5-Chloro-3-acetylthiophene-2-sulfonamide; 2-Sulfamoyl-5-chlorothiophene-3-yl methyl ketone; 1-(5-Chloro-2-sulfamoylthiophen-3-yl)ethanone; 3-Acetyl-5-chloro-2-thiophenesulfonamide; 5-Chloro-3-acetyl-2-thiophenesulfonamide; 160982-10-5; 3-Acetyl-5-chlorothiophene-2-sulfonylamide
EINECS	Contact for details

Quality Control

Our 3-Acetyl-5-Chlorothiophene-2-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.