Description

4-Bromo-2,6-Difluoroiodobenzene is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and iodine substituents on a benzene ring, makes it a versatile and valuable precursor for constructing complex molecules. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms can enhance biological activity and metabolic stability.
• Ligand & Catalyst Synthesis: Serves as a precursor for synthesizing sophisticated ligands and organometallic catalysts used in cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Material Science: Employed in the creation of organic electronic materials, such as semiconductors for OLEDs and OFETs, due to its halogenated aromatic core.
• Fluorinated Compound Library: An essential building block for medicinal chemistry and discovery chemistry programs focused on creating libraries of fluorinated compounds for high-throughput screening.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes, leveraging the reactivity of the iodine atom for further functionalization.

Basic Information

Product Name	4-Bromo-2,6-Difluoroiodobenzene
CAS No.	160976-02-3
Molecular Formula	C6H2BrF2I
Molecular Weight	318.89 g/mol
Synonyms	1-Bromo-3,5-difluoro-4-iodobenzene; 2,6-Difluoro-4-bromoiodobenzene; Benzene, 4-bromo-2,6-difluoro-1-iodo-; 4-Bromo-2,6-difluoro-1-iodobenzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2,6-Difluoroiodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.