Description

Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Amino-6-(Methylthio)-, (2-Endo,6-Exo)- (9Ci) is a high-purity, structurally complex chiral building block featuring a norbornane core with amino and methylthio functionalities. This compound is valued for its rigid, three-dimensional scaffold which is critical for imparting specific stereochemistry and conformational constraints in advanced molecular synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and synthesis of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where its unique structure can contribute to target specificity and metabolic stability.
• Asymmetric Catalysis Ligand Precursor: Acts as a starting material for synthesizing specialized chiral ligands used in asymmetric synthesis.
• Material Science Research: Employed in the creation of advanced polymers and specialty chemicals with tailored physical properties.
• Peptidomimetics & Bioactive Molecule Design: The constrained norbornane framework is utilized to mimic peptide turns and create structurally defined bioactive compounds.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Amino-6-(Methylthio)-, (2-Endo,6-Exo)- (9Ci)
CAS No.	160798-12-9
Molecular Formula	C9H15NO2S
Molecular Weight	201.28 g/mol
Synonyms	2-Amino-6-(methylthio)bicyclo[2.2.1]heptane-2-carboxylic acid; (2-Endo,6-Exo)-2-Amino-6-(methylthio)-2-norbornanecarboxylic acid; 2-Aza-6-thia-3-bicyclo[2.2.1]heptanecarboxylic acid derivative; Amino-methylthio-norbornanecarboxylic acid; NSC 339586; (1R,2S,4R)-2-Amino-6-(methylthio)bicyclo[2.2.1]heptane-2-carboxylic acid; Chiral norbornane amino acid derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through a suite of analytical techniques including HPLC, chiral HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.