Description

tert-Butyldimethyl(2-(thiophen-2-yl)ethoxy)silane is a specialized organosilicon compound featuring a thiophene moiety, serving as a crucial building block in advanced organic synthesis and materials science. Its primary value lies in its role as a versatile protecting group or precursor for the controlled functionalization of sensitive molecules, particularly in the synthesis of complex pharmaceuticals and electronic materials. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries who require reliable, high-quality reagents for demanding synthetic applications.

Application

• Pharmaceutical Intermediate: Key protecting group reagent in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for alcohols and polyfunctional molecules.
• Agrochemical Synthesis: Used as a precursor or functionalizing agent in the development of novel herbicides, fungicides, and insecticides.
• Material Science & Organic Electronics: Serves as a precursor for self-assembled monolayers (SAMs) or as a modifying agent for surfaces in OLED and OFET device fabrication.
• Complex Natural Product Synthesis: Employed in academic and industrial research for the stereoselective synthesis of complex natural products and fine chemicals.
• Polymer Modification: Acts as a functional silane coupling agent to introduce thiophene groups into polymer backbones, modifying electronic or physical properties.
• Chemical Research & Development: A valuable tool for chemists exploring new synthetic methodologies, particularly in silicon chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	tert-Butyldimethyl(2-(thiophen-2-yl)ethoxy)silane
CAS No.	160744-11-6
Molecular Formula	C12H22OSSi
Molecular Weight	242.45 g/mol
Synonyms	2-(2-Thienyl)ethoxy-tert-butyldimethylsilane; tert-Butyldimethyl[2-(2-thienyl)ethoxy]silane; TBDMS-2-thiopheneethanol ether; 2-(2-Thienyl)ethyl tert-butyldimethylsilyl ether; Silane, tert-butyldimethyl[2-(2-thienyl)ethoxy]-; (2-(Thiophen-2-yl)ethoxy)(tert-butyl)dimethylsilane; TBDMS ether of 2-thiopheneethanol
EINECS	Contact for details

Quality Control

Every batch of tert-Butyldimethyl(2-(thiophen-2-yl)ethoxy)silane undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Our quality assurance protocol includes GC, HPLC, and NMR analysis to verify identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment, ensuring full traceability and compliance with internal and customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.