Description

1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-[(4-Aminophenyl)Methyl]Hexahydro-2-Oxo-, (3As,4S,6Ar)- is a complex heterocyclic organic compound with significant synthetic utility. This specialized chemical serves as a key intermediate in the research and development of novel pharmaceutical agents, particularly those targeting specific enzymatic pathways. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of advanced active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of proprietary drug candidates, especially in medicinal chemistry programs.
• Bioconjugation Research: Utilized in the development of antibody-drug conjugates (ADCs) or other targeted therapies due to its reactive functional groups.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the design of inhibitors for specific protease enzymes.
• Chemical Biology Probes: Used to create molecular probes for studying biological processes and target validation in early-stage drug discovery.
• Academic & Institutional Research: Employed in university and research institute laboratories for investigating new synthetic methodologies and heterocyclic chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanamide, n-[(4-Aminophenyl)Methyl]Hexahydro-2-Oxo-, (3As,4S,6Ar)-
CAS No.	160624-42-0
Molecular Formula	C19H24N4O2S
Molecular Weight	372.48 g/mol
Synonyms	Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide, N-[(4-aminophenyl)methyl]-, (3aS,4S,6aR)-; (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide, N-[(4-aminophenyl)methyl]-; (3aS,4S,6aR)-N-[(4-Aminophenyl)methyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide; 160624-42-0; Biotin-PABA conjugate intermediate; Biotinyl-4-aminobenzoic acid precursor.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.