Description

(+/-)-3,4-Methylenedioxyethylamphetamine-D6 is a deuterated analog of a substituted phenethylamine, specifically designed for use as an analytical reference standard. This compound is of critical importance for ensuring the accuracy and reliability of quantitative analyses in forensic and clinical toxicology. It is primarily needed by analytical laboratories, forensic science institutions, and pharmaceutical research organizations engaged in method development and validation for substance detection and quantification.

Application

• Internal Standard for Mass Spectrometry (MS): Serves as a crucial internal standard in GC-MS or LC-MS/MS analysis for the quantification of its non-deuterated counterpart, correcting for instrument variability and sample preparation losses.
• Forensic Toxicology: Used in the development and validation of analytical methods for the precise identification and measurement of controlled substances in biological matrices.
• Clinical Research: Supports pharmacokinetic and metabolic studies by enabling accurate tracking and measurement of target analytes in complex samples.
• Method Development & Validation: Essential for establishing sensitive, specific, and reproducible analytical protocols in compliance with regulatory guidelines.
• Quality Control in Reference Material Production: Acts as a calibrant or system suitability check for laboratories manufacturing certified reference materials.
• Pharmaceutical Impurity Profiling: Can be utilized in research settings to study degradation pathways or synthesize labeled metabolites for analytical purposes.

Basic Information

Product Name	(+/-)-3,4-Methylenedioxyethylamphetamine-D6
CAS No.	160227-44-1
Molecular Formula	C12H9D6NO2
Molecular Weight	207.28 g/mol (for C12H9D6NO2)
Synonyms	MDEA-d6; 3,4-Methylenedioxy-N-ethylamphetamine-d6; N-Ethyl-3,4-methylenedioxyamphetamine-d6; Ethylenedioxyethylamphetamine-D6; 3,4-(Methylenedioxy)-N-ethylamphetamine-D6; (±)-MDEA-D6; 1-(1,3-Benzodioxol-5-yl)-N-ethylpropan-2-amine-D6; N-Ethyl-MDA-D6
EINECS	Contact for details

Quality Control

Our deuterated analytical standards are produced and verified under strict quality-controlled conditions to ensure the highest isotopic purity and chemical integrity. Each batch is characterized using advanced spectroscopic and chromatographic techniques, including NMR and HPLC/MS. A comprehensive Certificate of Analysis (COA) is provided, detailing the isotopic enrichment (typically ≥98% D), chemical purity (by HPLC), and analytical data. We support compliance with ISO/IEC 17025 standards for testing laboratories.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent moisture condensation. Store in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.