Description

1-(4-Brom-2-Methylphenyl)-1H-Pyrrole-2,5-Dione is a specialized heterocyclic organic compound featuring a maleimide core substituted with a brominated and methylated phenyl ring. This unique structure makes it a valuable high-purity chemical intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, particularly in the development of kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting specific enzymes and receptors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive maleimide moiety.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialized polymers with tailored thermal or mechanical properties.
• Bioconjugation Chemistry: Utilized for labeling proteins, peptides, or other biomolecules due to the selective reactivity of the maleimide group with thiols.
• Organic Synthesis: Acts as a versatile electrophile in Michael additions and other C–N or C–C bond-forming reactions for creating diverse chemical libraries.

Basic Information

Product Name	1-(4-Brom-2-Methylphenyl)-1H-Pyrrole-2,5-Dione
CAS No.	160207-20-5
Molecular Formula	C11H8BrNO2
Molecular Weight	266.09 g/mol
Synonyms	1-(4-Bromo-2-methylphenyl)-1H-pyrrole-2,5-dione; 4-Bromo-2-methylphenylmaleimide; N-(4-Bromo-2-methylphenyl)maleimide; 1-(4-Bromo-o-tolyl)-1H-pyrrole-2,5-dione; Maleimide, N-(4-bromo-2-methylphenyl)-; 160207-20-5; 1-(4-Brom-2-methylphenyl)maleimide
EINECS	Contact for details

Quality Control

Our production of 1-(4-Brom-2-Methylphenyl)-1H-Pyrrole-2,5-Dione adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP and ISO 9001 aligned practices for traceability and documentation, ensuring the material meets the exacting standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.