Description

2,6-Methano-1H-Pyrrolizin-8-Amine,Hexahydro-,Stereoisomer(9Ci) is a complex, stereochemically defined heterocyclic amine building block. This compound is valued for its rigid, three-dimensional structure, making it a critical intermediate in the synthesis of advanced pharmaceutical candidates and fine chemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its unique bicyclic amine structure.
• Ligand Synthesis: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & Industrial R&D: A valuable tool compound for medicinal chemistry programs and structure-activity relationship (SAR) studies.
• Peptidomimetics: Used to incorporate constrained, non-natural amino acid motifs into peptide analogs to enhance stability and bioavailability.

Basic Information

Product Name	2,6-Methano-1H-Pyrrolizin-8-Amine,Hexahydro-,Stereoisomer(9Ci)
CAS No.	159996-18-6
Molecular Formula	C8H14N2
Molecular Weight	138.21 g/mol
Synonyms	Hexahydro-2,6-methano-1H-pyrrolizin-8-amine stereoisomer; 8-Aminohexahydro-2,6-methano-1H-pyrrolizine; 1-Azabicyclo[3.3.0]octan-3-amine; 3-Amino-1-azabicyclo[3.3.0]octane; Octahydro-2,6-methanopyrrolizin-8-amine; Bicyclic pyrrolizidine amine; Stereoisomer of C8H14N2 (159996-18-6)
EINECS	Contact for details

Quality Control

Our 2,6-Methano-1H-Pyrrolizin-8-Amine,Hexahydro-,Stereoisomer(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure consistency and compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.