Description

(6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl)Methanol is a high-value fluorinated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring a trifluoroethoxy side chain, is engineered to impart unique electronic and steric properties essential for developing novel active compounds. This product is primarily targeted at research and development teams within the pharmaceutical and agrochemical sectors, where it is used to create new drug candidates and crop protection agents with enhanced efficacy and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoroethoxy group can improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals for electronic and optical applications.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl)Methanol
CAS No.	159981-20-1
Molecular Formula	C8H8F3NO2
Molecular Weight	207.15 g/mol
Synonyms	3-(Hydroxymethyl)-6-(2,2,2-trifluoroethoxy)pyridine; 6-(2,2,2-Trifluoroethoxy)-3-pyridinemethanol; (6-(Trifluoroethoxy)pyridin-3-yl)methanol; 5-(Hydroxymethyl)-2-(2,2,2-trifluoroethoxy)pyridine; 2-(2,2,2-Trifluoroethoxy)-5-(hydroxymethyl)pyridine; 3-Pyridinemethanol, 6-(2,2,2-trifluoroethoxy)-; CAS 159981-20-1
EINECS	Contact for details

Quality Control

Every batch of (6-(2,2,2-Trifluoroethoxy)Pyridin-3-Yl)Methanol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by HPLC, NMR, and GC-MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.