Description

Bicyclo[3.1.0]Hex-3-En-2-One, 4-(Hydroxymethyl)-1-(1-Methylethyl)-, (1R)- (9Ci) is a high-value, chiral bicyclic ketone derivative, distinguished by its unique fused ring structure and hydroxymethyl functional group. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis, enabling the construction of complex molecular architectures with precise stereochemical control. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and specialty fine chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Asymmetric Catalysis: Serves as a sophisticated ligand precursor or a chiral scaffold in the development of novel catalysts for enantioselective reactions.
• Agrochemical Synthesis: Used in the research and production of advanced, stereochemically-defined pesticides and herbicides.
• Fine Chemical Building Block: Employed in academic and industrial R&D for constructing natural product analogs and other high-value specialty chemicals.
• Flavor & Fragrance Chemistry: Potential intermediate for creating complex, bicyclic odorant and flavorant molecules.
• Material Science Research: Investigated as a monomer or cross-linking agent for novel polymers with specific thermal or mechanical properties.

Basic Information

Product Name	Bicyclo[3.1.0]Hex-3-En-2-One, 4-(Hydroxymethyl)-1-(1-Methylethyl)-, (1R)- (9Ci)
CAS No.	159645-34-8
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	(1R)-4-(Hydroxymethyl)-1-isopropylbicyclo[3.1.0]hex-3-en-2-one; (1R)-1-Isopropyl-4-(hydroxymethyl)bicyclo[3.1.0]hex-3-en-2-one; (+)-4-(Hydroxymethyl)-1-isopropylbicyclo[3.1.0]hex-3-en-2-one; (R)-4-(Hydroxymethyl)-1-(1-methylethyl)bicyclo[3.1.0]hex-3-en-2-one; Bicyclo[3.1.0]hex-3-en-2-one, 4-(hydroxymethyl)-1-(1-methylethyl)-, (1R)-; 159645-34-8; (R)-1-Isopropyl-4-(hydroxymethyl)bicyclo[3.1.0]hex-3-en-2-one
EINECS	Contact for details

Quality Control

Our production of Bicyclo[3.1.0]Hex-3-En-2-One, 4-(Hydroxymethyl)-1-(1-Methylethyl)-, (1R)- (9Ci) adheres to stringent quality protocols suitable for GMP-aligned applications. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, potency, and impurity profiles meet exacting customer specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.