Description

tert-Butyl 2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine]-1'-Carboxylate is a high-value, protected spirocyclic amine building block essential for modern pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, enabling the exploration of novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the development of central nervous system (CNS) and oncology drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic and fused heterocyclic compounds in drug discovery programs.
• CNS Drug Development: Employed in the synthesis of potential therapeutics targeting neurological disorders.
• Oncology Research: Serves as a building block for molecules designed to modulate specific biological pathways involved in cancer.
• Chemical Biology: Utilized in the creation of molecular probes to study protein function and enzyme activity.
• Process Chemistry: Investigated for scalable synthesis routes in the optimization of manufacturing processes for candidate drugs.

Basic Information

Product Name	tert-Butyl 2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine]-1'-Carboxylate
CAS No.	159634-80-7
Molecular Formula	C18H24N2O2
Molecular Weight	300.40 g/mol
Synonyms	1'-Boc-1,2,3,4-tetrahydrospiro[isoquinoline-4,4'-piperidine]; tert-Butyl 1,2,3,4-tetrahydrospiro[isoquinoline-4,4'-piperidine]-1'-carboxylate; 1,2,3,4-Tetrahydrospiro[isoquinoline-4,4'-piperidine]-1'-carboxylic acid tert-butyl ester; 1'-Boc-1,2,3,4-tetrahydrospiro[isoquinoline-4,4'-piperidine]; Spiro[isoquinoline-4,4'-piperidine]-1'-carboxylic acid, 2,3-dihydro-1H-, 1,1-dimethylethyl ester; Boc-Spiropiperidine-Isoquinoline
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,3-Dihydro-1H-Spiro[Isoquinoline-4,4'-Piperidine]-1'-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.