Description

Phenyl 4,6-o-Benzylidene-1-Thio-A-D-Mannopyranoside is a specialized thioglycoside derivative, a key building block in synthetic carbohydrate chemistry. This compound is valued for its role as a protected glycosyl donor or acceptor, enabling the stereoselective synthesis of complex oligosaccharides and glycoconjugates. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly those developing novel therapeutics, vaccines, and diagnostic tools that target carbohydrate-mediated biological processes.

Application

• Glycoconjugate Synthesis: A crucial intermediate for the chemical and enzymatic synthesis of biologically active glycoconjugates, including glycoproteins and glycolipids.
• Pharmaceutical Research: Used in the development of carbohydrate-based drugs, such as antiviral agents, anti-inflammatory compounds, and cancer therapeutics that mimic natural carbohydrate structures.
• Vaccine Development: Serves as a building block for constructing antigenic carbohydrate epitopes used in conjugate vaccine candidates against bacterial pathogens.
• Enzyme Substrate/Inhibitor Studies: Employed as a substrate or inhibitor in biochemical assays to study the function of glycosidases, glycosyltransferases, and lectins.
• Chemical Biology Probes: Utilized to create labeled or tagged carbohydrate probes for investigating cell-surface interactions and signaling pathways.
• Material Science: Potential applications in creating functionalized surfaces or polymers with specific carbohydrate motifs for biosensing or biocompatibility studies.

Basic Information

Product Name	Phenyl 4,6-o-Benzylidene-1-Thio-A-D-Mannopyranoside
CAS No.	159407-19-9
Molecular Formula	C20H20O5S
Molecular Weight	372.44 g/mol
Synonyms	Phenyl 4,6-O-Benzylidene-1-thio-α-D-mannopyranoside; 1-Thio-α-D-mannopyranoside, phenyl 4,6-O-(phenylmethylene)-; Phenyl 1-Thio-α-D-mannopyranoside 4,6-O-benzylidene acetal; 4,6-O-Benzylidene-α-D-mannopyranosyl phenyl sulfide; α-D-Mannopyranoside, phenyl 4,6-O-benzylidene-1-thio-; 1-S-Phenyl-4,6-O-benzylidene-1-thio-α-D-mannopyranoside
EINECS	Contact for details

Quality Control

Our Phenyl 4,6-o-Benzylidene-1-Thio-A-D-Mannopyranoside is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.