Description

2-(4-Fluorophenyl)-3-Butyn-2-Ol is a versatile fluorinated alkyne alcohol building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a fluorinated aromatic ring and a terminal alkyne group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic materials.
• Click Chemistry: The terminal alkyne group enables its use in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for catalysis and molecular recognition studies.
• Chemical Biology Probes: Acts as a precursor for fluorescent tags or other probes used in biochemical and cellular research.

Basic Information

Product Name	2-(4-Fluorophenyl)-3-Butyn-2-Ol
CAS No.	159028-51-0
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	4-Fluoro-α-methylbenzeneacetylenylcarbinol; 1-(4-Fluorophenyl)-1-methyl-2-propyn-1-ol; 2-(4-Fluorophenyl)-3-butyn-2-ol; 4-Fluoro-α-methylphenylacetylenylcarbinol; 1-(4-Fluorophenyl)-1-methylprop-2-yn-1-ol; 2-Butyn-2-ol, 2-(4-fluorophenyl)-; 4-Fluoro-α-methylbenzeneacetylenylcarbinol
EINECS	Contact for details

Quality Control

Our 2-(4-Fluorophenyl)-3-Butyn-2-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.