Description

1-[(4-Hydroxy-3,5-Dimethylbenzoyl)Oxy]-2,5-Pyrrolidinedione is a specialized organic compound belonging to the class of activated esters, specifically a derivative of N-hydroxysuccinimide (NHS). This compound matters as a high-performance coupling reagent and a key intermediate in the synthesis of amides, peptides, and other complex molecules, offering excellent reactivity and selectivity. It is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in advanced organic synthesis, bioconjugation, and the production of active pharmaceutical ingredients (APIs).

Application

• As a key coupling reagent in peptide synthesis and amide bond formation.
• An essential intermediate in the production of advanced pharmaceutical compounds and active ingredients (APIs).
• Used in bioconjugation chemistry for labeling proteins, antibodies, and other biomolecules.
• Employed in the synthesis of polymer precursors and specialty materials.
• Facilitates cross-linking reactions in material science and surface functionalization.
• Serves as a reagent in diagnostic kit development and assay formulations.

Basic Information

Product Name	1-[(4-Hydroxy-3,5-Dimethylbenzoyl)Oxy]-2,5-Pyrrolidinedione
CAS No.	158788-56-8
Molecular Formula	C13H13NO5
Molecular Weight	263.25 g/mol
Synonyms	4-Hydroxy-3,5-dimethylbenzoic acid N-hydroxysuccinimide ester; 3,5-Dimethyl-4-hydroxybenzoic acid succinimidyl ester; HDMBS-NHS; NHS ester of 4-hydroxy-3,5-dimethylbenzoic acid; 4-Hydroxy-3,5-dimethylbenzoyloxysuccinimide; N-Succinimidyl 4-hydroxy-3,5-dimethylbenzoate; 1-[(4-Hydroxy-3,5-dimethylbenzoyl)oxy]pyrrolidine-2,5-dione
EINECS	Contact for details

Quality Control

Our 1-[(4-Hydroxy-3,5-Dimethylbenzoyl)Oxy]-2,5-Pyrrolidinedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.