Description

Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Hydroxy-, (1S-Exo)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid, functionalized norbornane skeleton makes it a valuable precursor for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas requiring complex, constrained molecular frameworks.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where the specific stereochemistry and rigid structure can influence biological activity and environmental stability.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands and organocatalysts used in enantioselective transformations.
• Material Science Monomer: Potential use in the synthesis of specialized polymers with unique thermal and mechanical properties derived from the strained bicyclic system.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic chemistry and for studying structure-activity relationships (SAR).

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Hydroxy-, (1S-Exo)- (9Ci)
CAS No.	158568-27-5
Molecular Formula	C8H12O3
Molecular Weight	156.18 g/mol
Synonyms	(1S,2R,4S)-Bicyclo[2.2.1]heptane-2-carboxylic acid, 2-hydroxy-; (1S-exo)-2-Hydroxybicyclo[2.2.1]heptane-2-carboxylic acid; exo-2-Hydroxy-2-norbornanecarboxylic acid, (1S)-; L-2-Hydroxynorbornane-2-carboxylic acid; endo,exo-2-Hydroxybicyclo[2.2.1]heptane-2-carboxylic acid (specific isomer); 2-Norbornanecarboxylic acid, 2-hydroxy-, (1S-exo)-; Chiral Norbornane Derivative
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, 2-Hydroxy-, (1S-Exo)- (9Ci) is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for the specific grade.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.