Description

Ethyl 5-Chloro-1-(Phenylsulfonyl)-1H-Indole-2-Carboxylate is a high-purity, synthetically valuable indole derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in providing a functionalized indole scaffold essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients. Its specific substitution pattern makes it a versatile intermediate for medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory pathways, and oncological targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the indole core's bioactivity.
• Chemical Biology Probe Synthesis: Employed to create molecular tools for studying enzyme function and cellular signaling pathways.
• Material Science Research: Acts as a monomer or functional unit in the development of specialty polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects.
• Academic Research: Utilized in university and institutional laboratories for methodological development in heterocyclic and sulfonamide chemistry.

Basic Information

Product Name	Ethyl 5-Chloro-1-(Phenylsulfonyl)-1H-Indole-2-Carboxylate
CAS No.	158561-88-7
Molecular Formula	C17H14ClNO4S
Molecular Weight	363.81 g/mol
Synonyms	Ethyl 5-chloro-1-(phenylsulfonyl)indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 5-chloro-1-(phenylsulfonyl)-, ethyl ester; 5-Chloro-1-(phenylsulfonyl)indole-2-carboxylic acid ethyl ester; 158561-88-7; Ethyl 5-chloro-1-(benzenesulfonyl)-1H-indole-2-carboxylate; 1-Benzenesulfonyl-5-chloro-indole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-1-(Phenylsulfonyl)-1H-Indole-2-Carboxylate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.