Description

Ethyl 2-Amino-5-tert-Butylthiophene-3-Carboxylate is a high-purity organic building block and heterocyclic intermediate of significant commercial importance. This compound is valued for its role in the synthesis of complex molecules, particularly in advanced pharmaceutical research and material science. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and pesticides, leveraging its thiophene core structure.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as conductive polymers and organic semiconductors.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and pigments where the thiophene moiety imparts specific color or stability properties.
• Chemical Research (R&D): A versatile reagent for academic and industrial research in organic synthesis and heterocyclic chemistry.
• Ligand and Catalyst Development: The amino and ester functional groups make it a useful precursor for creating custom ligands in coordination chemistry and catalysis.

Basic Information

Item	Detail
Product Name	Ethyl 2-Amino-5-tert-Butylthiophene-3-Carboxylate
CAS No.	158461-00-8
Molecular Formula	C11H17NO2S
Molecular Weight	227.32 g/mol
Synonyms	2-Amino-5-tert-butylthiophene-3-carboxylic acid ethyl ester; Ethyl 5-tert-butyl-2-aminothiophene-3-carboxylate; 5-tert-Butyl-2-aminothiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-(1,1-dimethylethyl)-, ethyl ester; ATBCE; 158461-00-8
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-5-tert-Butylthiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.