Description

Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-7-Mercapto-4-Methyl-, [4R-(4-α-,7-α-,8A-Ba-)]- (9Ci) is a high-purity, stereochemically defined heterocyclic compound featuring a mercapto functional group. This compound matters as a sophisticated chiral building block and key intermediate for pharmaceutical research and development, enabling the synthesis of complex molecules with potential biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral scaffold in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Research: Used as a building block for developing new active ingredients in crop protection and pest management products.
• Chemical Biology Probe: Utilized in medicinal chemistry to study enzyme interactions and receptor binding due to its unique heterocyclic structure and thiol functionality.
• Peptidomimetic Synthesis: Acts as a constrained, non-natural amino acid analog in the design of peptide-like molecules with enhanced stability and bioavailability.
• Catalyst Ligand Precursor: The mercapto group can be utilized to develop novel ligands for asymmetric catalysis in fine chemical synthesis.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in heterocyclic and stereoselective chemistry.

Basic Information

Product Name	Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-7-Mercapto-4-Methyl-, [4R-(4-α-,7-α-,8A-Ba-)]- (9Ci)
CAS No.	158393-29-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(4R,7R,8aS)-Hexahydro-7-mercapto-4-methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one; Hexahydro-7-mercapto-4-methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one, (4R,7R,8aS)-; (4R,7R,8aS)-7-Mercapto-4-methylhexahydro-1H-pyrrolo[1,2-a]pyrazin-1-one; 158393-29-4; Pyrrolo[1,2-a]pyrazin-1(2H)-one, hexahydro-7-mercapto-4-methyl-, (4R,7R,8aS)-; (4R,7R,8aS)-4-Methyl-7-sulfanylhexahydro-1H-pyrrolo[1,2-a]pyrazin-1-one
EINECS	Contact for details

Quality Control

Our Pyrrolo[1,2-A]Pyrazin-1(2H)-One, Hexahydro-7-Mercapto-4-Methyl-, [4R-(4-α-,7-α-,8A-Ba-)]- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research-grade specifications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. For long-term storage, temperatures of 2-8°C are recommended to maintain stability. Keep away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.