Description

(4R)-4-Butyl-2-Oxazolidinone is a high-purity, chiral oxazolidinone derivative widely utilized as a versatile chiral auxiliary and building block in asymmetric synthesis. Its value lies in enabling the stereoselective construction of complex molecules, which is critical for producing enantiomerically pure pharmaceuticals and advanced materials. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality chiral intermediates.

Application

• As a chiral auxiliary in Evans-type asymmetric alkylation, aldol, and Diels-Alder reactions.
• Key intermediate in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs).
• Building block for the development of novel agrochemicals and fine chemicals.
• Use in academic and industrial research for methodological development in organic synthesis.
• Potential precursor for ligands and catalysts used in asymmetric catalysis.
• Component in the synthesis of complex natural products and bioactive molecules.

Basic Information

Product Name	(4R)-4-Butyl-2-Oxazolidinone
CAS No.	158249-50-4
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(R)-4-Butyl-2-oxazolidinone; (4R)-4-Butyloxazolidin-2-one; (R)-(-)-4-Butyl-2-oxazolidinone; (R)-4-n-Butyl-2-oxazolidinone; Evans Auxiliary Derivative; (R)-N-Butyryloxazolidinone; Butanoic acid, 2-oxo-, (4R)-4-butyl-2-oxo-3-oxazolidinyl ester (related); (R)-4-Butyl-1,3-oxazolidin-2-one
EINECS	Contact for details

Quality Control

Our (4R)-4-Butyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee reproducible performance and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.