Description

7H-Purine-6-Thiol is a high-purity, sulfur-containing purine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical building block for the development of novel therapeutic agents and biochemical probes. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications ranging from drug discovery to nucleotide chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of purine-based active pharmaceutical ingredients (APIs) and nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for investigating metabolic pathways involving purines.
• Nucleotide Chemistry: Serves as a foundational scaffold for modifying nucleosides and nucleotides to study structure-activity relationships.
• Agrochemical Development: Employed in research for creating novel plant growth regulators or pesticides based on heterocyclic chemistry.
• Material Science: Potential use as a ligand or building block in the synthesis of specialized coordination polymers or metal-organic frameworks (MOFs).

Basic Information

Product Name	7H-Purine-6-Thiol
CAS No.	157930-13-7
Molecular Formula	C5H4N4S
Molecular Weight	152.18 g/mol
Synonyms	6-Mercaptopurine (Tautomer); Purine-6-thiol; 6-Thiopurine; 6-Sulfanylpurine; 6-Mercapto-7H-purine; 1,7-Dihydro-6H-purine-6-thione; 6-Purinethiol; NSC 755
EINECS	Contact for details

Quality Control

Our 7H-Purine-6-Thiol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity, the material should be handled under an inert atmosphere to minimize oxidation and stored away from incompatible substances.

Specification

Item	Specification
Appearance	Yellow to pale brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.