Description

(4R)-4-Propyl-2-Oxazolidinone CAS NO 157922-13-9 is a high-purity chiral oxazolidinone derivative, a critical building block in asymmetric synthesis. Its primary value lies in its role as a versatile chiral auxiliary and precursor for the synthesis of complex, biologically active molecules. This compound is essential for research and production chemists in the pharmaceutical and agrochemical industries, where precise stereochemistry is paramount for product efficacy and safety.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, antibacterial, and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis Auxiliary: Used as a chiral controller in aldol, alkylation, and Diels-Alder reactions to induce high enantioselectivity.
• Agrochemical Research: Serves as a precursor for novel chiral pesticides and herbicides, where specific stereoisomers often exhibit enhanced activity and lower environmental impact.
• Ligand and Catalyst Development: A starting material for synthesizing novel chiral ligands and organocatalysts used in fine chemical manufacturing.
• Academic & Process R&D: Employed in university and industrial laboratories for methodological development and scale-up studies in stereoselective synthesis.

Basic Information

Item	Details
Product Name	(4R)-4-Propyl-2-Oxazolidinone
CAS No.	157922-13-9
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	(R)-4-Propyl-2-oxazolidinone; (4R)-4-Propyl-1,3-oxazolidin-2-one; (R)-(-)-4-Propyl-2-oxazolidinone; 4-Propyl-2-oxazolidinone, (4R)-; Propyloxazolidinone; Evans Auxiliary Derivative; Chiral Oxazolidinone Auxiliary
EINECS	Contact for details

Quality Control

Our (4R)-4-Propyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.