Description

(Z)-1-[4-(2-Chloroethoxyphenyl)]-1,2-Diphenyl-1-Butene-4,4,5,5,5-D5 is a high-purity, deuterated organic compound of significant interest in advanced chemical research and development. Its primary value lies in its role as a stable isotope-labeled intermediate, which is critical for creating internal standards in analytical chemistry and for tracing metabolic pathways in life sciences. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require precise, isotopically labeled building blocks for synthesis and analysis.

Application

• Pharmaceutical Research: Used as a deuterium-labeled intermediate in the synthesis of novel drug candidates and metabolites for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Analytical Chemistry: Serves as a critical internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the accurate quantification of target analytes.
• Metabolic Pathway Tracing: Enables detailed investigation of biochemical pathways and mechanisms in both in vitro and in vivo studies due to its isotopic label.
• Agrochemical Development: Employed in the research and synthesis of labeled pesticides or herbicides to study environmental fate, degradation, and residue analysis.
• Material Science Research: Potential use as a specialized monomer or precursor in the development of advanced polymers with unique properties.
• Contract Research Organizations (CROs): Supplied to CROs conducting bioanalytical testing and custom synthesis services for global clients.

Basic Information

Product Name	(Z)-1-[4-(2-Chloroethoxyphenyl)]-1,2-Diphenyl-1-Butene-4,4,5,5,5-D5
CAS No.	157738-49-3
Molecular Formula	C24H17D5ClO
Molecular Weight	~372.94 g/mol
Synonyms	(Z)-1-[4-(2-Chloroethoxy)phenyl]-1,2-diphenyl-1-butene-4,4,5,5,5-d5; (Z)-Tamoxifen-d5 Impurity/Intermediate; 1-Butene, 1-[4-(2-chloroethoxy)phenyl]-1,2-diphenyl-, (Z)-, 4,4,5,5,5-d5; cis-1-[4-(2-Chloroethoxyphenyl)]-1,2-Diphenyl-1-Butene-4,4,5,5,5-D5; Deuterated Chlorotrianisene Analog; Isotope-labeled Triphenylethylene Derivative; [D5]-(Z)-1-(4-(2-Chloroethoxy)phenyl)-1,2-diphenyl-1-butene
EINECS	Contact for details

Quality Control

Every batch of (Z)-1-[4-(2-Chloroethoxyphenyl)]-1,2-Diphenyl-1-Butene-4,4,5,5,5-D5 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity through comprehensive analytical techniques including NMR, HPLC, and Mass Spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity (assay), isotopic enrichment, and impurity profiles to ensure it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Chemical Purity (NMR)	≥ 97.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.