Description

(2-Bromo-3-Thienyl)Methylamine Hydrochloride is a high-purity organic building block and pharmaceutical intermediate. This compound is valued for its role as a versatile synthon in the construction of complex heterocyclic molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides that incorporate the thiophene moiety for enhanced biological activity.
• Material Science: Serves as a precursor for functionalized monomers or ligands in the creation of conductive polymers, organic semiconductors, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Acts as a versatile reagent for introducing the 2-bromo-3-aminomethylthiophene scaffold into more complex molecular architectures via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig).
• Bioconjugation & Probe Development: The amine hydrochloride group facilitates its use in creating fluorescent probes, bioconjugates, or affinity labels for biochemical and diagnostic applications.

Basic Information

Product Name	(2-Bromo-3-Thienyl)Methylamine Hydrochloride
CAS No.	157664-47-6
Molecular Formula	C5H7BrClNS
Molecular Weight	228.53 g/mol
Synonyms	1-(2-Bromo-3-thienyl)methanamine hydrochloride; (2-Bromo-3-thienylmethyl)amine hydrochloride; 2-Bromo-3-(aminomethyl)thiophene hydrochloride; 1-(2-Bromo-thiophen-3-yl)-methylamine hydrochloride; 3-(Aminomethyl)-2-bromothiophene hydrochloride; 2-Bromo-3-thiophenemethylamine HCl; α-Amino-2-bromo-3-thiophenemethane hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Bromo-3-Thienyl)Methylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.