Description

(2-Bromoethyl)(Trityl)Sulfane is a specialized organosulfur compound featuring a trityl-protected thiol group, making it a valuable building block in synthetic organic chemistry. Its primary value lies in its role as a protected thiol precursor, enabling controlled deprotection for the introduction of sulfur-containing functional groups in complex molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) containing thioether or sulfhydryl groups.
• Peptide Chemistry: Used in the preparation of cysteine analogs and for introducing thiol-protecting groups in solid-phase peptide synthesis (SPPS).
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to functionalize polymers and resins with thiol-reactive sites for advanced material properties.
• Chemical Biology Probes: Useful in the development of bioconjugation reagents and probes for studying protein function.
• Agrochemical Research: Intermediate in the synthesis of novel herbicides, fungicides, and insecticides that utilize sulfur chemistry.

Basic Information

Product Name	(2-Bromoethyl)(Trityl)Sulfane
CAS No.	157522-54-8
Molecular Formula	C21H19BrS
Molecular Weight	383.34 g/mol
Synonyms	2-Bromoethyl Trityl Sulfide; Trityl 2-Bromoethyl Sulfide; (2-Bromoethyl)triphenylmethyl Sulfane; 1-Bromo-2-(tritylthio)ethane; Triphenylmethyl 2-Bromoethyl Sulfide; S-(2-Bromoethyl) Trityl Thioether; 157522-54-8; SCHEMBL11827679
EINECS	Contact for details

Quality Control

Every batch of (2-Bromoethyl)(Trityl)Sulfane is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥95% (by HPLC/NMR), with detailed impurity profiling available. A comprehensive Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, identity confirmation, and levels of specific impurities. We support cGMP production for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.