Description

3'-Dc Cep CAS NO 157327-96-3 is a high-purity nucleoside derivative, specifically a cytidine analog, used as a critical building block in oligonucleotide synthesis. This compound is essential for the research and development of novel therapeutic agents, including antisense oligonucleotides and siRNA, due to its role in modifying genetic material. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions focused on genetic medicine and molecular biology.

Application

• Oligonucleotide Synthesis: A key phosphoramidite monomer for the solid-phase synthesis of modified DNA and RNA strands.
• Antisense Therapy Development: Used in the research and production of antisense oligonucleotides designed to target specific mRNA sequences.
• siRNA and miRNA Research: Serves as a modified nucleotide in the construction of small interfering RNA (siRNA) and microRNA (miRNA) for gene silencing studies.
• Diagnostic Probe Fabrication: Incorporated into nucleic acid probes for diagnostic assays and hybridization techniques.
• Pharmaceutical Intermediate: Acts as a sophisticated intermediate in the synthesis of more complex nucleoside-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed in studies investigating nucleic acid structure, function, and enzyme interactions.

Basic Information

Product Name	3'-Dc Cep
CAS No.	157327-96-3
Molecular Formula	C14H19N3O5
Molecular Weight	309.32 g/mol
Synonyms	3'-Deoxycytidine CEP; 3'-Deoxycytidine Cyclic Ester Phosphoramidite; 3'-Deoxycytidine, 5'-(2-cyanoethyl N,N-diisopropylphosphoramidite); 3'-Deoxycytidine Phosphoramidite; Cytidine, 3'-deoxy-, 5'-[2-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]oxy]ethyl]; 3'-dC-CEP; 3'-dC Phosphoramidite; 3'-Deoxycytidine 5'-CE Phosphoramidite
EINECS	Contact for details

Quality Control

Our 3'-Dc Cep is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive pharmaceutical research. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere (e.g., nitrogen or argon) to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in acetonitrile, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.