Description

Tilidin-Phosphat is a phosphate salt derivative of the centrally acting analgesic Tilidine, identified by CAS NO 157163-65-0. This compound is a key pharmaceutical intermediate of significant interest for the development and production of controlled analgesic formulations. It is primarily required by advanced pharmaceutical manufacturers and research institutions engaged in the synthesis of potent pain management therapeutics.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of Tilidine-based analgesic APIs (Active Pharmaceutical Ingredients).
• Analgesic Formulation Development: Serves as a critical precursor in R&D for developing new or generic opioid agonist formulations.
• Reference Standard: Utilized as a high-purity chemical reference standard in analytical laboratories for quality control and method development.
• Clinical Research: Employed in preclinical and clinical studies investigating pain management pathways and drug efficacy.
• Controlled Drug Production: A controlled substance intermediate for licensed manufacturers producing scheduled analgesic medications.

Basic Information

Product Name	Tilidin-Phosphat
CAS No.	157163-65-0
Molecular Formula	C17H23NO5P
Molecular Weight	352.34 g/mol
Synonyms	Tilidine Phosphate; Tilidine Phosphate Salt; (±)-Ethyl trans-2-(dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylate phosphate; Tilidinium phosphate; UNII-9FWM488A6U; Tilidine phosphate (1:1); 157163-65-0
EINECS	Contact for details

Quality Control

Our Tilidin-Phosphat is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to current Good Manufacturing Practice (cGMP) principles where applicable, and the product meets stringent in-house specifications aligned with pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.