Description

Cyanomethylenetributylphosphorane is a specialized organophosphorus reagent, widely recognized for its utility as a versatile ylide in organic synthesis. Its primary value lies in facilitating the synthesis of complex molecules through Wittig and related olefination reactions, enabling the efficient construction of carbon-carbon double bonds. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing alkenes and other unsaturated moieties in active pharmaceutical ingredient (API) development.
• Agrochemical Production: Used in the synthesis of complex molecules for crop protection agents and herbicides.
• Advanced Material Research: Employed in the creation of novel polymers, liquid crystals, and organic electronic materials.
• Wittig Reaction Reagent: Serves as a stable ylide for the stereoselective formation of alkenes from carbonyl compounds.
• Academic & Industrial R&D: A valuable tool for methodology development and the synthesis of novel organic compounds in research laboratories.
• Fine Chemical Manufacturing: Used in the multi-step synthesis of specialty chemicals and complex fragrance or flavor intermediates.

Basic Information

Product Name	Cyanomethylenetributylphosphorane
CAS No.	157141-27-0
Molecular Formula	C₁₄H₂₈NP
Molecular Weight	241.36 g/mol
Synonyms	Tributyl(cyanomethylene)phosphorane; (Cyanomethylene)tributylphosphorane; Cyanomethylidenetributylphosphorane; Butyltriphenylphosphonium cyanomethylide (common name variant); Phosphorane, cyanomethylenetributyl-; Phosphorane, (cyanomethylene)tributyl-; CMBP (abbreviation); Tributylphosphonium cyanomethylide ylide
EINECS	Contact for details

Quality Control

Our Cyanomethylenetributylphosphorane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and hygroscopic (moisture-sensitive), it is recommended to store the material under an inert gas (argon or nitrogen) in a cool, dry place at 15-25°C. Minimize exposure to air and moisture during handling to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.