Description

Butyric-3,3,4,4,4-D5 Acid is a deuterium-labeled isotopologue of butyric acid, where five hydrogen atoms are replaced with deuterium, specifically at the 3,3,4,4,4 positions. This high isotopic purity is critical for applications requiring precise internal standards in mass spectrometry and NMR spectroscopy, ensuring accurate quantification and metabolic pathway tracing. It is an essential reagent for researchers and quality control laboratories in the pharmaceutical, agrochemical, and life science sectors, particularly for drug metabolism and pharmacokinetics (DMPK) studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analyses to ensure accuracy in pharmaceutical bioanalysis and environmental testing.
• Metabolic Pathway Tracing: Enables detailed investigation of fatty acid metabolism and short-chain fatty acid (SCFA) functions in nutritional, microbiological, and biomedical research.
• NMR Spectroscopy Studies: Serves as a probe in nuclear magnetic resonance (NMR) for studying molecular structure, dynamics, and reaction mechanisms without signal interference from protons.
• Pharmaceutical Development: Critical for drug metabolism and pharmacokinetics (DMPK) studies, aiding in the development and regulatory submission of new therapeutic agents.
• Agrochemical Research: Employed in the study of pesticide and herbicide degradation pathways and environmental fate.
• Chemical Synthesis Intermediate: Acts as a labeled building block for the synthesis of more complex deuterated compounds for research and diagnostic purposes.

Basic Information

Product Name	Butyric-3,3,4,4,4-D5 Acid
CAS No.	156779-02-1
Molecular Formula	C4D5HO2 or C4H3D5O2
Molecular Weight	93.13 g/mol
Synonyms	Butanoic-3,3,4,4,4-d5 Acid; [3,3,4,4,4-2H5]Butyric Acid; Deuterated Butyric Acid (D5, 98%); Propyl-3,3,4,4,4-d5 Carboxylic Acid; Butyric Acid-d5; 3,3,4,4,4-Pentadeuteriobutanoic Acid; Butanoic-d5 Acid; 4,4,4-Trideuterio-3,3-dideuterobutanoic Acid
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure high chemical and isotopic purity. Each batch is characterized using advanced analytical techniques including NMR, MS, and HPLC. Certificates of Analysis (COA) are provided, detailing parameters such as chemical purity, isotopic enrichment (Atom % D), and solvent content. We support compliance with various research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (Atom % D)	≥ 98% (by 1H NMR or MS)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.