Description

5-Bromo-8-Nitro-1,2,3,4-Tetrahydroisoquinoline is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular scaffold, featuring both bromo and nitro substituents, makes it a versatile precursor for constructing complex nitrogen-containing compounds. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Organic Synthesis Reagent: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromo substituent.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	5-Bromo-8-Nitro-1,2,3,4-Tetrahydroisoquinoline
CAS No.	156694-04-1
Molecular Formula	C9H9BrN2O2
Molecular Weight	257.09 g/mol
Synonyms	5-Bromo-8-nitro-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-5-bromo-8-nitroisoquinoline; 5-Bromo-8-nitro-3,4-dihydro-1H-isoquinoline; 8-Nitro-5-bromo-1,2,3,4-tetrahydroisoquinoline; 156694-04-1
EINECS	Contact for details

Quality Control

Our 5-Bromo-8-Nitro-1,2,3,4-Tetrahydroisoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.