Description

4-Benzyloxy-2,3-Difluorobenzeneboronic Acid is a high-purity, synthetically valuable boronic acid derivative, serving as a critical building block in modern organic synthesis. Its primary value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require a reliable, high-quality reagent for developing active pharmaceutical ingredients (APIs) and functional organic compounds.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in fluorinated bioactive molecules.
• Agrochemical Research: Used in the development of advanced, fluorinated pesticides and herbicides, leveraging the stability and reactivity of the boronic acid group.
• Material Science: Serves as a monomer or building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed as a versatile reagent for introducing the 4-benzyloxy-2,3-difluorophenyl moiety into more complex molecular architectures.
• Life Sciences & Diagnostics: Potential use in synthesizing probes, sensors, and other tools for biochemical research and diagnostic applications.

Basic Information

Product Name	4-Benzyloxy-2,3-Difluorobenzeneboronic Acid
CAS No.	156635-87-9
Molecular Formula	C₁₃H₁₁BF₂O₃
Molecular Weight	264.04 g/mol
Synonyms	2,3-Difluoro-4-(phenylmethoxy)benzeneboronic Acid; (4-(Benzyloxy)-2,3-difluorophenyl)boronic Acid; 4-(Benzyloxy)-2,3-difluorobenzeneboronic Acid; B-(4-Benzyloxy-2,3-difluorophenyl)boronic Acid; 156635-87-9; 4-Benzyloxy-2,3-difluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2,3-Difluorobenzeneboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques like HPLC, NMR, and mass spectrometry. Our quality management system is designed to meet the stringent requirements of research and development as well as scale-up production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.