Description

1-Isoquinolineacetic Acid,1,2,3,4-Tetrahydro-,Methyl Ester,(R)- (9Ci) is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel therapeutic agents, including potential central nervous system (CNS) drugs and alkaloid derivatives.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to create enantiomerically pure compounds for high-value applications.
• Agrochemical Research: Serves as a precursor in the development of new pesticides and herbicides with targeted activity.
• Fine Chemical Production: Employed in the manufacture of complex dyes, pigments, and other specialty organic materials.
• Academic & R&D: Used in chemical research for methodological development and the study of isoquinoline chemistry and stereochemistry.
• Ligand and Catalyst Development: Potential use in the synthesis of chiral ligands for catalytic systems.

Basic Information

Product Name	1-Isoquinolineacetic Acid,1,2,3,4-Tetrahydro-,Methyl Ester,(R)- (9Ci)
CAS No.	156545-91-4
Molecular Formula	C₁₃H₁₅NO₂
Molecular Weight	217.26 g/mol
Synonyms	(R)-1,2,3,4-Tetrahydro-1-isoquinolineacetic Acid Methyl Ester; Methyl (R)-1,2,3,4-Tetrahydro-1-isoquinolineacetate; (R)-Methyl 1,2,3,4-Tetrahydroisoquinoline-1-acetate; (R)-Tetrahydropapaverine Acid Methyl Ester Derivative; (R)-THIQ-AA Methyl Ester; (R)-1,2,3,4-Tetrahydroisoquinoline-1-acetic Acid Methyl Ester; (R)-1-Carboxymethyl-1,2,3,4-tetrahydroisoquinoline Methyl Ester
EINECS	Contact for details

Quality Control

Our 1-Isoquinolineacetic Acid,1,2,3,4-Tetrahydro-,Methyl Ester,(R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.