Description

1H-Pyrrole, 3-Fluoro-1-[Tris(1-Methylethyl)Silyl]- is a high-value organosilicon-protected pyrrole derivative, specifically functionalized with a fluorine atom at the 3-position. This compound is critical for advanced organic synthesis, serving as a key protected intermediate that enables selective functionalization of the pyrrole ring system under demanding reaction conditions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in the development of fluorinated heterocycles with potential biological activity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the fluoropyrrole moiety can enhance stability and bioavailability.
• Material Science Research: Serves as a precursor for functionalized polymers, conductive materials, and organic electronic components due to the tunable electronic properties of the pyrrole core.
• Organometallic Chemistry: Acts as a ligand or a protected substrate in catalytic reactions and metal complex formation.
• Custom Synthesis & Contract Manufacturing: An essential reagent for fine chemical and custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	1H-Pyrrole, 3-Fluoro-1-[Tris(1-Methylethyl)Silyl]-
CAS No.	156304-02-8
Molecular Formula	C13H26FNSi
Molecular Weight	243.44 g/mol
Synonyms	3-Fluoro-1-(triisopropylsilyl)pyrrole; 1-(Triisopropylsilyl)-3-fluoropyrrole; 3-Fluoro-1H-pyrrole, 1-[tris(1-methylethyl)silyl]-; 3-Fluoropyrrole, 1-triisopropylsilyl-; N-Triisopropylsilyl-3-fluoropyrrole; TIPS-3-fluoropyrrole; 3-Fluoro-N-(triisopropylsilyl)pyrrole
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrole, 3-Fluoro-1-[Tris(1-Methylethyl)Silyl]- is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your critical synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.