Description

Methyl 3-Amino-4-(4-Fluorophenyl)Thiophene-2-Carboxylate is a high-value, multi-functional heterocyclic building block featuring a thiophene core substituted with an amino group and a fluorinated aromatic ring. This compound is critically important for its role as a key synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily sought after by research scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of drug candidates targeting a range of therapeutic areas, including central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Serves as a building block for developing new generation herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the research and development of organic semiconductors, conductive polymers, and advanced organic electronic materials due to its thiophene-based structure.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring novel chemical reactions.
• Ligand and Catalyst Development: The amino and ester functional groups make it a valuable starting point for synthesizing specialized ligands for metal catalysis.

Basic Information

Product Name	Methyl 3-Amino-4-(4-Fluorophenyl)Thiophene-2-Carboxylate
CAS No.	156274-32-7
Molecular Formula	C12H10FNO2S
Molecular Weight	251.28 g/mol
Synonyms	Methyl 3-amino-4-(4-fluorophenyl)thiophene-2-carboxylate; 3-Amino-4-(4-fluorophenyl)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-4-(4-fluorophenyl)-, methyl ester; Methyl 3-amino-4-(p-fluorophenyl)thiophene-2-carboxylate; 4-(4-Fluorophenyl)-3-aminothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-4-(4-Fluorophenyl)Thiophene-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Light yellow to beige crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.