Description

Acetamide, n-(Octahydro-1,7,8-Trihydroxy-6-Indolizinyl)-n-(Phenylmethyl)-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, stereochemically defined organic compound belonging to the indolizidine alkaloid family. This molecule matters as a high-value synthetic intermediate and a key scaffold for pharmaceutical research, offering a unique polyhydroxylated structure for targeted drug design. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutics, particularly in areas like glycosidase inhibition and antiviral research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.
• Glycosidase Inhibitor Research: The polyhydroxylated indolizidine core is a key structural motif for developing potent glycosidase inhibitors, relevant for metabolic and antiviral therapies.
• Medicinal Chemistry Scaffold: Used as a sophisticated template for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Biochemical Research: Employed as a reference standard or tool compound in enzymatic studies and biochemical assays.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for constructing complex natural product analogs and chiral molecules.

Basic Information

Product Name	Acetamide, n-(Octahydro-1,7,8-Trihydroxy-6-Indolizinyl)-n-(Phenylmethyl)-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156206-16-5
Molecular Formula	C21H30N2O4
Molecular Weight	374.48 g/mol
Synonyms	N-[(1S,6R,7R,8R,8aR)-Octahydro-1,7,8-trihydroxy-6-indolizinyl]-N-(phenylmethyl)acetamide; N-Benzyl-N-[(1S,6R,7R,8R,8aR)-octahydro-1,7,8-trihydroxy-6-indolizinyl]acetamide; (1S,6R,7R,8R,8aR)-N-Benzyl-N-(octahydro-1,7,8-trihydroxy-6-indolizinyl)acetamide; Polyhydroxylated Indolizidine Acetamide Derivative; Indolizidine Alkaloid Intermediate
EINECS	Contact for details

Quality Control

Our high-purity Acetamide derivative is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.