Description

1,6,7,8-Indolizinetetrol, Octahydro-, 6-Methanesulfonate, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a high-purity, stereochemically defined indolizine derivative with significant synthetic utility. This compound serves as a critical chiral building block and advanced intermediate for the development of complex organic molecules. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams focused on creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in alkaloid and heterocyclic chemistry.
• Organic Synthesis Building Block: Used in multi-step synthesis to construct complex molecular architectures with defined stereochemistry.
• Academic & Contract Research: Essential for chemical biology studies, methodology development, and exploring new reaction pathways in academic and industrial research laboratories.
• Agrochemical Research: Potential intermediate for the synthesis of novel, biologically active compounds in crop protection research.
• Catalyst & Ligand Development: Serves as a precursor for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1,6,7,8-Indolizinetetrol, Octahydro-, 6-Methanesulfonate, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156206-15-4
Molecular Formula	C10H18O7S
Molecular Weight	282.31 g/mol
Synonyms	(1S,6R,7S,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol 6-Methanesulfonate; 1S-(1α,6β,7α,8β,8aβ)-Octahydro-1,6,7,8-indolizinetetrol 6-(Methylsulfonate); 6-O-Mesyl-1,6,7,8-tetrahydroxyoctahydroindolizine (1S-isomer); CAS 156206-15-4; Indolizine-tetrol methanesulfonate derivative; Chiral indolizine mesylate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.