Description

1,7,8-Indolizinetriol, Octahydro-6-(2-Methoxyethyl)Amino-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, stereochemically defined indolizine derivative with significant potential in advanced organic synthesis and pharmaceutical research. This compound is valued for its unique polyhydroxylated and amino-substituted structure, which serves as a versatile chiral building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for complex target molecules.
• Organic Synthesis Building Block: Utilized in multi-step synthesis for constructing intricate indolizine-based frameworks and natural product analogs.
• Biochemical Research: Potential use as a precursor or standard in biochemical studies exploring enzyme inhibitors or receptor ligands.
• Asymmetric Catalysis Studies: Serves as a substrate or ligand precursor in the development of new asymmetric synthetic methodologies.
• Fine Chemical Production: Employed in the pilot-scale and commercial-scale manufacture of specialized, high-value chemical products.

Basic Information

Product Name	1,7,8-Indolizinetriol, Octahydro-6-(2-Methoxyethyl)Amino-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156205-83-3
Molecular Formula	C13H25NO5
Molecular Weight	275.34 g/mol
Synonyms	(1S,6R,7S,8R,8aR)-Octahydro-6-[(2-methoxyethyl)amino]-1,7,8-indolizinetriol; 6-(2-Methoxyethyl)amino-octahydro-1,7,8-indolizinetriol; (1S,6R,7S,8R,8aR)-6-[(2-Methoxyethyl)amino]octahydro-1,7,8-indolizinetriol; 1S-(1α,6β,7α,8β,8aβ)-Octahydro-6-[(2-methoxyethyl)amino]-1,7,8-indolizinetriol; Indolizinetriol derivative CAS 156205-83-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical-grade materials. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are available upon request, and we adhere to a cGMP-compliant quality management system for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Long-term storage under inert atmosphere (e.g., nitrogen or argon) is recommended for optimal preservation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.