Description

1,7,8-Indolizinetriol, Octahydro-6-(2-Methylpropyl)Amino-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, stereochemically defined indolizine derivative with significant potential as a key synthetic intermediate or pharmacological scaffold. Its intricate polyhydroxylated structure and chiral centers make it valuable for advanced research and development in fine chemical synthesis. This compound is primarily sought by pharmaceutical R&D teams and specialty chemical manufacturers working on novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its complex, functionalized indolizine ring system.
• Biochemical Probe Development: Acts as a precursor for developing tool compounds to study specific enzyme interactions or biological mechanisms.
• Fine Chemical Synthesis: Employed in multi-step synthetic routes to create high-value, complex natural product analogs or specialty chemicals.
• Academic Research: Utilized in universities and research institutes for studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	1,7,8-Indolizinetriol, Octahydro-6-(2-Methylpropyl)Amino-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156205-77-5
Molecular Formula	C11H23N1O3
Molecular Weight	217.31 g/mol
Synonyms	(1S,6S,7R,8R,8aR)-Octahydro-6-[(2-methylpropyl)amino]-1,7,8-indolizinetriol; 6-(Isobutylamino)octahydro-1,7,8-indolizinetriol; (1S,6S,7R,8R,8aR)-6-(2-Methylpropylamino)octahydroindolizine-1,7,8-triol; 1S-(1α,6β,7α,8β,8aβ)-Octahydro-6-[(2-methylpropyl)amino]-1,7,8-indolizinetriol; Indolizinetriol derivative (CAS 156205-77-5)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. We provide comprehensive analytical data, including HPLC purity, chiral purity confirmation, and structural verification via spectroscopic methods. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for identity, purity, and impurities. Our quality systems are designed to support cGMP and ISO guidelines for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. Long-term storage under inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.