Description

Methanesulfonic Acid, Trifluoro-, 1,7,8-Tris(Acetyloxy)Octahydro-6-Indolizinyl Ester, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a specialized, high-purity synthetic intermediate with a complex, functionalized indolizine core. This compound matters for its role as a key chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in complex alkaloid-like structures.
• Agrochemical Synthesis: Used in the synthesis of advanced, high-efficacy crop protection agents with specific stereochemical requirements.
• Organic Synthesis Research: Serves as a versatile building block in academic and industrial R&D for constructing intricate heterocyclic compounds.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of fine chemicals and active pharmaceutical ingredients (APIs).
• Catalyst and Ligand Precursor: Potential use in the development of novel chiral catalysts or ligands for asymmetric synthesis.

Basic Information

Product Name	Methanesulfonic Acid, Trifluoro-, 1,7,8-Tris(Acetyloxy)Octahydro-6-Indolizinyl Ester, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156205-67-3
Molecular Formula	C18H22F3NO8S
Molecular Weight	469.43 g/mol
Synonyms	1S-(1α,6β,7α,8β,8aβ)-1,7,8-Tris(acetyloxy)octahydro-6-indolizinyl trifluoromethanesulfonate; (1S,6R,7S,8R,8aR)-1,7,8-Triacetoxyindolizidin-6-yl Triflate; Indolizidine-6-yl Triflate Triacetate; Trifluoromethanesulfonic Acid 1,7,8-Tris(acetyloxy)octahydro-6-indolizinyl Ester (1S-isomer); 6α-Triflyloxyindolizidine-1β,7α,8β-triyl Triacetate; CAS 156205-67-3; Advanced Indolizidine Chiral Intermediate; Chiral Indolizidinyl Triflate Ester.
EINECS	Contact for details

Quality Control

Our Methanesulfonic Acid, Trifluoro-, 1,7,8-Tris(Acetyloxy)Octahydro-6-Indolizinyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chiral purity and assay, to ensure it meets the high standards required for research and process development. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from moisture and direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.