Description

1,7,8-Indolizinetriol, 6-Aminooctahydro-, Triacetate (Ester), 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a high-purity, stereochemically defined indolizine derivative, serving as a critical advanced intermediate in pharmaceutical synthesis. Its complex, functionalized structure makes it a valuable building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for use in process development and the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Process Chemistry: Serves as a standardized building block for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• Fine Chemical Synthesis: Employed in the production of specialized agrochemicals or high-value performance materials requiring precise stereochemistry.
• Bioconjugation & Probe Development: Potential use in creating labeled compounds or molecular probes for biochemical and diagnostic research due to its amine and hydroxyl functionalities.

Basic Information

Product Name	1,7,8-Indolizinetriol, 6-Aminooctahydro-, Triacetate (Ester), 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156205-51-5
Molecular Formula	C16H25NO6
Molecular Weight	327.37 g/mol
Synonyms	(1S,6R,7R,8R,8aR)-6-Aminooctahydro-1,7,8-indolizinetriol Triacetate; 6-Amino-1,7,8-indolizinetriol Triacetate (1S,6R,7R,8R,8aR)-; 1S-(1α,6β,7α,8β,8aβ)-6-Aminooctahydro-1,7,8-indolizinetriol Triacetate; 6-Aminooctahydroindolizinetriol Triacetate; SW 163C; SW-163C; SW163C; (1S,6R,7R,8R,8aR)-6-Azaniumyloctahydro-1,7,8-indolizinetriol Triacetate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols to ensure batch-to-batch consistency and purity for sensitive synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We employ analytical methods including HPLC, GC, and chiral analysis to verify the compound meets exacting specifications, supporting its use in cGMP-compliant pharmaceutical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.