Description

1H-Pyrrolizine-1,2,7-Triol, 3-(Azidomethyl)Hexahydro-, Triacetate (Ester), 1R-(1.Alpha.,2.Beta.,3.Alpha.,7.Beta.,7A.Alpha.)- is a high-purity, specialized pyrrolizine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique functionalized structure, featuring both azide and triacetate protecting groups, makes it an invaluable building block for the development of complex bioactive molecules. This compound is essential for research and development teams in the pharmaceutical and agrochemical industries, particularly those focused on creating novel nitrogen-containing heterocycles and targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in neurological and metabolic disorder pathways.
• Click Chemistry Reagent: The azidomethyl group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, facilitating rapid library synthesis for drug discovery.
• Agrochemical Synthesis: Used in the development of novel herbicides and insecticides, leveraging the pyrrolizine core's bioactivity.
• Academic & Contract Research: Serves as a valuable tool compound for synthetic methodology development and mechanistic studies in university and CRO laboratories.
• Bioconjugation & Probe Development: Employed in the synthesis of chemical probes and bioconjugates for biochemical and diagnostic applications.

Basic Information

Item	Details
Product Name	1H-Pyrrolizine-1,2,7-Triol, 3-(Azidomethyl)Hexahydro-, Triacetate (Ester), 1R-(1.Alpha.,2.Beta.,3.Alpha.,7.Beta.,7A.Alpha.)-
CAS No.	156205-50-4
Molecular Formula	C16H22N4O6
Molecular Weight	366.37 g/mol
Synonyms	(1R,2R,3S,7S,7aR)-3-(Azidomethyl)hexahydro-1H-pyrrolizine-1,2,7-triyl triacetate; 1R-(1α,2β,3α,7β,7aα)-3-(Azidomethyl)hexahydro-1H-pyrrolizine-1,2,7-triol triacetate; 3-(Azidomethyl)hexahydro-1H-pyrrolizine-1,2,7-triyl triacetate; Pyrrolizine triacetate azide derivative; CAS 156205-50-4
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolizine-1,2,7-Triol, 3-(Azidomethyl)Hexahydro-, Triacetate (Ester) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, verified by advanced analytical techniques including HPLC, NMR, and MS.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.