Description

1,7,8-Indolizinetriol, 6-Azidooctahydro-, Triacetate (Ester), 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, stereochemically defined azido-functionalized indolizine derivative, serving as a highly versatile synthetic intermediate for advanced organic synthesis. Its unique molecular architecture, featuring multiple protected hydroxyl groups and a reactive azide moiety, makes it a critical building block for constructing complex nitrogen-containing heterocycles and bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for applications in medicinal chemistry and chemical biology.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially for nitrogen-rich heterocyclic scaffolds with potential biological activity.
• Click Chemistry Reagent: The azide group enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation, polymer modification, and materials science.
• Agrochemical Research: Building block for developing new active ingredients with complex, multi-functional molecular structures.
• Medicinal Chemistry Probe: Used to explore structure-activity relationships (SAR) and synthesize analogs for biological screening.
• Chemical Biology Tool: Facilitates the labeling and study of biomolecules through bioorthogonal chemistry techniques.
• Academic & R&D Synthesis: Valuable for methodological studies and the total synthesis of complex natural products or designed molecules.

Basic Information

Product Name	1,7,8-Indolizinetriol, 6-Azidooctahydro-, Triacetate (Ester), 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156205-49-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6-Azidooctahydro-1,7,8-indolizinetriol triacetate; (1S,6R,7S,8R,8aR)-6-Azidooctahydro-1,7,8-indolizinetriol 1,7,8-triacetate; 1S-(1α,6β,7α,8β,8aβ)-6-Azidooctahydro-1,7,8-indolizinetriol Triacetate; 6-Azido-1,7,8-triacetoxyindolizidine (stereospecific); CAS 156205-49-1; Azido-functionalized indolizine triacetate; Stereoisomer of indolizinetriol azido triacetate.
EINECS	Contact for details

Quality Control

Our production of 1,7,8-Indolizinetriol, 6-Azidooctahydro-, Triacetate (Ester) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS to confirm identity, stereochemical purity, and assay. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support development and cGMP-compliant production needs with comprehensive documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is light-sensitive; containers should be opaque or kept in dark conditions. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.