Description

1,6,7,8-Indolizinetetrol, Octahydro-, 1,7,8-Triacetate, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a high-purity, stereochemically defined indolizine derivative with the CAS registry number 156205-42-4. This compound is a critical advanced pharmaceutical intermediate or building block for the synthesis of complex bioactive molecules. It is primarily sought by research institutions and pharmaceutical development teams working on novel therapeutic agents, particularly in areas requiring sophisticated polycyclic frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, especially those with indolizidine or related alkaloid structures.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex, polyfunctionalized molecules due to its multiple hydroxyl and acetate-protected functional groups.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new chemical entities targeting various biological pathways.
• Process Chemistry Development: Utilized in scaling up synthetic routes for active pharmaceutical ingredients (APIs) where this specific stereochemistry is required.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in related synthetic processes.

Basic Information

Product Name	1,6,7,8-Indolizinetetrol, Octahydro-, 1,7,8-Triacetate, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	156205-42-4
Molecular Formula	C14H22O7
Molecular Weight	302.32 g/mol
Synonyms	(1S,6R,7S,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol 1,7,8-Triacetate; 1,6,7,8-Tetrahydroxyoctahydroindolizine 1,7,8-Triacetate; 1S-(1α,6β,7α,8β,8aβ)-Octahydro-1,6,7,8-indolizinetetrol 1,7,8-Triacetate; SW 163B; SW-163B; Indolizine-1,7,8-triol, octahydro-1,6,7,8-tetrahydroxy-, 1,7,8-triacetate, (1S,6R,7S,8R,8aR)-; (1S,6R,7S,8R,8aR)-1,7,8-Triacetoxyoctahydro-1,6,7,8-indolizinetetrol
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure full traceability and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.